HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Bromide → Methyl-phenyl-(3-styryl-1H-indazol-6-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Bromide | HCID 253877 | — |
| Reactant | 6-iodo-3-styryl-1-[2-(trimethyl-silanyl)ethoxymethyl]-1H-indazole | HCID 69370147 | — |
| Reactant | methyl-phenyl-(3-styryl-1-[2-(trimethyl-silanyl)-ethoxymethyl]-1H-indazol-6-yl)-amine | HCID 69370392 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | Methyl-phenyl-(3-styryl-1H-indazol-6-yl)-amine | HCID 69371726 | — |
Reaction Steps
6-Iodo-3-styryl-1-[2-(trimethyl-silanyl)-ethoxymethyl]-1H-indazole was converted to methyl-phenyl-{3-styryl-1-[2-(trimethyl-silanyl)-ethoxymethyl]-1H-indazol-6-yl}-amine as described in Example 11, step (v). Rf sm 0.35 Rf p 0.13 (EtOAc:hexane 1:9); IR (KBr) 3031, 2951, 1625, 1595, 1498, 1449, 1326, 1303, 1248, 1212, 1076, 835, 694 cm−1; MS (ESI) [M+H]/z Calc'd 456. Found 456.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141587B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-fe39b3d093a2495491c9cf1f6f546a4e |
| Source note | uspto-grants-2006_11 |