HCID 69370211, compound → HCID 69370452, compound

HRID 724389Notes

Reaction equation

HRID 724389 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]=[CH:11][C:12]3[C:20]4[C:15](=[CH:16][C:17]([N:21]([CH3:31])[C:22]5[CH:27]=[CH:26][CH:25]=[C:24]([N+:28]([O-])=O)[CH:23]=5)=[CH:18][CH:19]=4)[N:14](COCC[Si](C)(C)C)[N:13]=3)=[CH:9][C:4]=2[O:3][CH2:2]1.O1C2C=CC(C=CC3C4C(=CC(N(C)C5C=CC=C([N+]([O-])=O)C=5)=CC=4)NN=3)=CC=2OC1>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]=[CH:11][C:12]3[C:20]4[C:15](=[CH:16][C:17]([N:21]([CH3:31])[C:22]5[CH:27]=[CH:26][CH:25]=[C:24]([NH2:28])[CH:23]=5)=[CH:18][CH:19]=4)[NH:14][N:13]=3)=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

3

Reactant 2

HCID 69370211HCID 69370211, compoundHCID 69372789HCID 69372789, compound

Product 1

HCID 69370452HCID 69370452, compound

Procedure

{3-(2-Benzo[1,3]dioxol-5-yl-vinyl)-1-[2-(trimethyl-silanyl)-ethoxymethyl]-1H-indazol-6-yl}-methyl-(3-nitro-phenyl)-amine was converted to [3-(2-Benzo[1,3]dioxol-5-yl-vinyl)-1H-indazol-6-yl]-methyl-(3-nitro-phenyl)-amine as described in Example 11. LCMS (ESI) [M+H]/z Calc'd 415. found 415. Anal. Calc'd: C, 66.66; H, 4.38; N, 13.52. Found: C, 66.56; H. 4.48; N, 13.35.

Sources & evidence

ORD record
ord-6fd2bc0b30234269a7e952cf050520b0
Source dataset
uspto-grants-2006_11
Patent number
US07141587B2

Reaction notes

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