HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-hydroxy-3-phenylpropanoate → 2-{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-hydroxy-3-phenylpropanoate | HCID 518800 | — |
| Reactant | HCID 9915604 | HCID 9915604 | — |
| Product | 2-{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid methyl ester | HCID 10439812 | — |
Reaction Steps
The title compound was prepared from 3,5-dibromo-4′-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-ol, and 3-phenyllactic acid methyl ester in substantially the same manner, as described in Example 7, and was obtained as a white solid, mp 70–72° C.; MS m/e 713 (M+);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141672B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-1922c1213bda4214b0454bff1afd09cd |
| Source note | uspto-grants-2006_11 |