Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 724454Generated: November 1, 2026

Methyl 2-hydroxy-3-phenylpropanoate → 2-{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid methyl ester

https://huagongshe.com/reaction/724454

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-hydroxy-3-phenylpropanoateHCID 518800—
ReactantHCID 9915604HCID 9915604—
Product2-{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid methyl esterHCID 10439812—

Reaction Steps

The title compound was prepared from 3,5-dibromo-4′-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-ol, and 3-phenyllactic acid methyl ester in substantially the same manner, as described in Example 7, and was obtained as a white solid, mp 70–72° C.; MS m/e 713 (M+);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141672B2
Source datasetuspto-grants-2006_11
ORD IDord-1922c1213bda4214b0454bff1afd09cd
Source noteuspto-grants-2006_11