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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 724529Generated: October 30, 2026

1,3-Propanediamine → (3-[(6-Nitro-1H-indole-2-carbonyl)-amino]-propyl)-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/724529

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-PropanediamineHCID 428—
ReactantMethyl 6-nitro-1H-indole-2-carboxylateHCID 11816863—
Reactant{2-[(6-Nitro-1H-indole-2-carbonyl)-amino]-ethyl}-carbamic acid tert-butyl esterHCID 58747124—
Product(3-[(6-Nitro-1H-indole-2-carbonyl)-amino]-propyl)-carbamic acid tert-butyl esterHCID 6959934695%

Reaction Steps

Compound 121 was prepared from compound 34 with 1,3-diaminopropane, followed by Boc-protection according to the procedure for compound 35. Yield: 95%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07141680B2
Source datasetuspto-grants-2006_11
ORD IDord-44894f950f714a208db5fb3d84d7496f
Source noteuspto-grants-2006_11