HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178513019, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Pyrazole-1-carboxamidine monohydrochloride | HCID 2734672 | — |
| Reactant | HCID 21880768 | HCID 21880768 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178513019 | HCID 178513019 | — |
Reaction Steps
170 mg (0.05 mmol) 131 was treated overnight with 73.5 mg (0.5 mmol) pyrazole-1-carboxamidine hydrochloride and 172 μL diisopropylethylamine dissolved in 2 mL DMF. Next day the resin was drained, washed five times with DMF to give 132 which was treated immediately to cleave the compound off, as described below in Example 121.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07141680B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-0db13cf4bbd6413ab4e89df648374a4c |
| Source note | uspto-grants-2006_11 |