HRID724534

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)c1cc2cc([N+](=O)[O-])ccc2[nH]1.O=C(O)c1cc2cc([N+](=O)[O-])ccc2o1

HCID86591610

未命名化合物

结构：N=C(N)NCCNC(=O)c1cc2cc(NC(=O)c3cc4cc(NC(=O)CNC(=N)N)ccc4[nH]3)ccc2[nH]1

HCID178513006

未命名化合物

结构：N=C(N)NCCNC(=O)c1cc2cc(NC(=O)c3cc4cc(NC(=O)CNC(=N)N)ccc4o3)ccc2[nH]1

HCID178513007

未命名化合物

PRODUCTS

生成物

结构：N=C(N)NCC(=O)Nc1ccc2[nH]c(C(=O)Nc3ccc4[nH]c(C(=O)NCCN)cc4c3)cc2c1

HCID178513018

未命名化合物

PROCEDURE

实验过程

Compound 137 was synthesized as described for Compound 135 in Example 116 through Example 122, except instead of 5-nitrobenzofuran-2-carboxylic acid 5-nitroindole-2-carboxylic acid was used. Yield: 15.4 mg (59%) of compound 138. MS: 518.24 (M+H+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-84f44387798c4473ac9a5011b63b0431
来源数据集: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07141680B2
来源说明: uspto-grants-2006_11

反应 SMILES

N(CCNC(C1NC2C(C=1)=CC(NC(C1OC3C=CC(NC(=O)CNC(N)=N)=CC=3C=1)=O)=CC=2)=O)C(N)=N.[N+](C1C=C2C(=CC=1)NC(C(O)=O)=C2)([O-])=O.[N+](C1C=CC2OC(C(O)=O)=CC=2C=1)([O-])=O.[NH:69]([CH2:73][CH2:74][NH:75][C:76]([C:78]1[NH:79][C:80]2[C:85]([CH:86]=1)=[CH:84][C:83]([NH:87][C:88]([C:90]1[NH:91][C:92]3[C:97]([CH:98]=1)=[CH:96][C:95]([NH:99][C:100](=[O:106])[CH2:101][NH:102][C:103]([NH2:105])=[NH:104])=[CH:94][CH:93]=3)=[O:89])=[CH:82][CH:81]=2)=[O:77])C(N)=N>>[NH2:69][CH2:73][CH2:74][NH:75][C:76]([C:78]1[NH:79][C:80]2[C:85]([CH:86]=1)=[CH:84][C:83]([NH:87][C:88]([C:90]1[NH:91][C:92]3[C:97]([CH:98]=1)=[CH:96][C:95]([NH:99][C:100](=[O:106])[CH2:101][NH:102][C:103]([NH2:105])=[NH:104])=[CH:94][CH:93]=3)=[O:89])=[CH:82][CH:81]=2)=[O:77]