HCID 86591610, compound → HCID 178513018, compound

HRID 724534Notes

Reaction equation

N(CCNC(C1NC2C(C=1)=CC(NC(C1OC3C=CC(NC(=O)CNC(N)=N)=CC=3C=1)=O)=CC=2)=O)C(N)=N.[N+](C1C=C2C(=CC=1)NC(C(O)=O)=C2)([O-])=O.[N+](C1C=CC2OC(C(O)=O)=CC=2C=1)([O-])=O.[NH:69]([CH2:73][CH2:74][NH:75][C:76]([C:78]1[NH:79][C:80]2[C:85]([CH:86]=1)=[CH:84][C:83]([NH:87][C:88]([C:90]1[NH:91][C:92]3[C:97]([CH:98]=1)=[CH:96][C:95]([NH:99][C:100](=[O:106])[CH2:101][NH:102][C:103]([NH2:105])=[NH:104])=[CH:94][CH:93]=3)=[O:89])=[CH:82][CH:81]=2)=[O:77])C(N)=N>>[NH2:69][CH2:73][CH2:74][NH:75][C:76]([C:78]1[NH:79][C:80]2[C:85]([CH:86]=1)=[CH:84][C:83]([NH:87][C:88]([C:90]1[NH:91][C:92]3[C:97]([CH:98]=1)=[CH:96][C:95]([NH:99][C:100](=[O:106])[CH2:101][NH:102][C:103]([NH2:105])=[NH:104])=[CH:94][CH:93]=3)=[O:89])=[CH:82][CH:81]=2)=[O:77]

Participants

Reactant 3

HCID 86591610HCID 86591610, compound

HCID 178513006HCID 178513006, compound

HCID 178513007HCID 178513007, compound

Product 1

HCID 178513018HCID 178513018, compound

Procedure

Compound 137 was synthesized as described for Compound 135 in Example 116 through Example 122, except instead of 5-nitrobenzofuran-2-carboxylic acid 5-nitroindole-2-carboxylic acid was used. Yield: 15.4 mg (59%) of compound 138. MS: 518.24 (M+H+).

Sources & evidence

ORD record: ord-84f44387798c4473ac9a5011b63b0431
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07141680B2

Reaction notes

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