5-Nitroindole-2-carboxylic acid → HCID 58747091, compound

HRID 724538Notes

Reaction equation

HRID 724538 reaction equation
[F:1][C:2]1[C:7]([O:8][C:9]([C:11]2[NH:12][C:13]3[C:18]([CH:19]=2)=[CH:17][C:16]([N+]([O-])=O)=[CH:15][CH:14]=3)=[O:10])=[C:6]([F:23])[C:5]([F:24])=[C:4]([F:25])[C:3]=1[F:26].[N+:27](C1C=C2C(=CC=1)NC(C(O)=O)=C2)([O-:29])=[O:28]>>[F:1][C:2]1[C:7]([O:8][C:9]([C:11]2[NH:12][C:13]3[C:18]([CH:19]=2)=[CH:17][CH:16]=[C:15]([N+:27]([O-:29])=[O:28])[CH:14]=3)=[O:10])=[C:6]([F:23])[C:5]([F:24])=[C:4]([F:25])[C:3]=1[F:26]

Participants

3

Reactant 2

HCID 3512915-Nitroindole-2-carboxylic acidHCID 21880759HCID 21880759, compound

Product 1

HCID 58747091HCID 58747091, compound

Procedure

Compound 192 was synthesized as described for Compound 105 in Example 93, except instead of 104, 191 was used. It was used without isolation.

Sources & evidence

ORD record
ord-61ca1e3f94404732a4758149bb824b53
Source dataset
uspto-grants-2006_11
Patent number
US07141680B2

Reaction notes

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