4-Bromobenzenesulfonamide → 4-(4-Hydroxymethylphenyl)phenylsulfonamide

HRID 724626Notes

Reaction equation

HRID 724626 reaction equation
CS([C:5]1[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][C:14]([CH2:17][OH:18])=[CH:13][CH:12]=2)[CH:8]=[CH:9][CH:10]=1)(=O)=O.BrC1C=CC([S:26]([NH2:29])(=[O:28])=[O:27])=CC=1>>[OH:18][CH2:17][C:14]1[CH:13]=[CH:12][C:11]([C:7]2[CH:6]=[CH:5][C:10]([S:26]([NH2:29])(=[O:28])=[O:27])=[CH:9][CH:8]=2)=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 696964-BromobenzenesulfonamideHCID 21879230(3'-Methanesulfonyl-biphenyl-4-yl)-methanol

Product 1

HCID 566046214-(4-Hydroxymethylphenyl)phenylsulfonamide

Procedure

This compound was prepared in a manner analogous to the preparation of (3′-methanesulfonyl-biphenyl-4-yl)-methanol (WO 01/70753, Example 27) using 4-bromo-benzenesulfonamide as the starting material. LCMS found for C13H13NO3SNa (M+Na)+: m/z=286.

Sources & evidence

ORD record
ord-7fa4a11014a341da894603fc0a1cbdb4
Source dataset
uspto-grants-2006_11
Patent number
US07141596B2

Reaction notes

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