Water → HCID 12762576, compound

Participants

Reaction Steps

Water (20 ml) and potassium carbonate (10.64 g) were added to a solution of benzyl dibenzyloxyacetate (11.15 g) in THF (80 ml) and the mixture heated under reflux for 24 hours. The mixture was allowed to cool, poured into water, extracted with ether, acidified with concentrated hydrochloric acid and again extracted with ether. The extract from acidic solution was washed with brine, dried (MgSO4) and evaporated under reduced pressure to give the sub-title compound (8.12 g), which was used crude in step c).

Provenance & Evidence