(2R)-2-(((tert-butoxy)carbonyl)amino)-3-methylbutanoic acid → HCID 86751835, compound

Participants

Reaction Steps

Coupling of 1-[5-[2(S)-(2,4-dichloro-5-methoxyphenoxy)-propionamido]-2,5-dideoxy-2-fluoro-β-D-arabinofuranosyl-5-ethyluracil with N-Boc-D-valine in a manner analogous to that described in Example 1(A) gave 1-[3-O-[N-(tert-butoxycarbonyl)-D-valyl]-5-[2(S)-(2,4-dichioro-5-methoxyphenoxy)-propionamido]-2,5-dideoxy-2-fluoro-β-D-arabinofuranosyl-5-ethyluracil as a white solid, m.p. 101° C. (dec.).

Provenance & Evidence