Methyl iodide → HCID 67846129, compound

HRID 724799Notes

Reaction equation

HRID 724799 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH2:22])[C:5]2[N:6]=[CH:7][N:8]([C:20]=2[N:21]=1)[C@@H:9]1[O:18][C@H:15]([CH2:16][OH:17])[C@@H:12]([O:13][CH3:14])[C@@:10]1([CH3:19])[OH:11].[CH3:23]I>>[CH3:1][C:2]1[N:3]=[C:4]([NH:22][CH3:23])[C:5]2[N:6]=[CH:7][N:8]([C:20]=2[N:21]=1)[C@@H:9]1[O:18][C@H:15]([CH2:16][OH:17])[C@@H:12]([O:13][CH3:14])[C@@:10]1([CH3:19])[OH:11]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 67642752HCID 67642752, compound

Product 1

HCID 67846129HCID 67846129, compound

Procedure

Compound 63 was methylated by methyl iodide and then rearranged to give 2,N6,2',3'-O-tetramethyladenosine (Compound 64).

Sources & evidence

ORD record
ord-1cd77ab12d32417c82715e425683244f
Source dataset
uspto-grants-1998_01
Patent number
US05705491

Reaction notes

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