HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → Benzenesulfonamide, N-(2-methylpropyl)-4-nitro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | 4-Nitrobenzenesulfonyl chloride | HCID 7404 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Benzenesulfonamide, N-(2-methylpropyl)-4-nitro- | HCID 3113406 | 70.1% |
Reaction Steps
To a solution of isobutylamine (5 mL, 0.052 mol) in CH2Cl2 (100 mL) was added Et3N (5.07 mL) and 4-nitrobenzenesulfonyl chloride (11.7 g, 0.052 mol) and the mixture was stirred at room temperature overnight. The resulting solution was washed with H2O (3×), dried and concentrated to afford the desired product (9.41 g, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05705504 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-1d4df52c72f543a6b1abcd0f96ff3c20 |
| Source note | uspto-grants-1998_01 |