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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 72491Generated: October 26, 2026

(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 67958313, compound

https://huagongshe.com/reaction/72491

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-Methyl 4-(1-aminoethyl)benzoate hydrochlorideHCID 57462942—
Reactant5-Chloro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acidHCID 67958861—
ProductHCID 67958313HCID 6795831380.2%

Reaction Steps

The title compound (D147) (90 mg) was prepared according to the experimental procedure described in Description 146 starting from 5-chloro-2-(3-(3-fluorophenoxy)azetidin-1-yl)nicotinic acid (D103) (75 mg, 0.232 mmol) and (S)-methyl 4-(1-aminoethyl)benzoate (D3) (50 mg, 0.232 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08828987B2
Source datasetuspto-grants-2014_09
ORD IDord-1be17149e7244ec0b4043f6c86687674
Source noteuspto-grants-2014_09