HCID 19711117, compound → HCID 15956322, compound

HRID 724947Notes

Reaction equation

HRID 724947 reaction equation
[CH3:1][C:2]1[CH:12]=[N:11][C:10]2[N:9]([CH2:13][CH3:14])[C:8]3[N:15]=[CH:16][C:17]([C:19]#[C:20][C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)=[CH:18][C:7]=3[C:6](=[O:27])[N:5]([CH3:28])[C:4]=2[C:3]=1[CH3:29]>[Pt]=O>[CH3:1][C:2]1[CH:12]=[N:11][C:10]2[N:9]([CH2:13][CH3:14])[C:8]3[N:15]=[CH:16][C:17]([CH2:19][CH2:20][C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)=[CH:18][C:7]=3[C:6](=[O:27])[N:5]([CH3:28])[C:4]=2[C:3]=1[CH3:29]

Participants

3

Reactant 1

HCID 19711117HCID 19711117, compound

Product 1

HCID 15956322HCID 15956322, compound

Reagents, catalysts & solvents 1

HCID 82844Platinum oxide (PtO)Catalyst

Procedure

The title compound was prepared by hydrogenation of 5,11-dihydro-3,4-dimethyl-11-ethyl-5-methyl-8-(phenylethynyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one over platinum oxide, as described in Example 42b. The product crystallized from ether/petroleum ether, m.p. 187°-188° C.

Workup

  1. customThe product crystallized from ether/petroleum ether, m.p. 187°-188° C.

Sources & evidence

ORD record
ord-be2981262bd140ee868df54450271664
Source dataset
uspto-grants-1998_01
Patent number
US05705499

Reaction notes

Loading…