HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl bromide → 4-Bromo-2-methyl-1-oxo-1lambda~5~-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl bromide | HCID 10482 | — |
| Reactant | Pyridine, 2-methyl-4-nitro-, 1-oxide | HCID 95291 | — |
| Product | 4-Bromo-2-methyl-1-oxo-1lambda~5~-pyridine | HCID 54446139 | 31.1% |
Reaction Steps
4-Nitro-2-picoline N-oxide (1.0 g, 6.5 mmol) was treated with acetyl bromide (3.5 mL, 47 mmol) as described in Example 65b to provide the title compound (0.38 g, 31%) as an orange-brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05705499 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-2c3f234abb6d47a89d4327c6dff4f47c |
| Source note | uspto-grants-1998_01 |