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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 72498Generated: October 26, 2026

Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → HCID 67958349, compound

https://huagongshe.com/reaction/72498

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(1-aminocyclopropyl)benzoate hydrochlorideHCID 66824369—
Reactant5-Chloro-2-(3-(2,4-difluorophenoxy)azetidin-1-yl)nicotinic acidHCID 67958422—
ProductHCID 67958349HCID 6795834944.6%

Reaction Steps

The title compound (D154) (55 mg) was prepared according to the experimental procedure described in Description 144 starting from 5-chloro-2-(3-(2,4-difluorophenoxy)azetidin-1-yl)nicotinic acid (D108) (82 mg, 0.240 mmol) and methyl 4-(1-aminocyclopropyl)benzoate (D7) (54.79 mg, 0.240 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08828987B2
Source datasetuspto-grants-2014_09
ORD IDord-bd62a4730b4b4d4baa0e50ecfa9f7c89
Source noteuspto-grants-2014_09