2-(7-bromo-5-methyl-1H-indol-3-yl)ethanamine hydrochloride → 5-Cyclohexyltryptamine hydrochloride

HRID 725047Notes

Reaction equation

HRID 725047 reaction equation
[ClH:1].[CH3:2][C:3]1[CH:14]=[C:13]2[C:6]([NH:7][CH:8]=[C:9]2[CH2:10][CH2:11][NH2:12])=[C:5](Br)[CH:4]=1.Cl.[CH:17]1(C2C=CC(NN)=CC=2)[CH2:22][CH2:21]C[CH2:19][CH2:18]1>>[ClH:1].[CH:2]1([C:3]2[CH:14]=[C:13]3[C:6]([NH:7][CH:8]=[C:9]3[CH2:10][CH2:11][NH2:12])=[CH:5][CH:4]=2)[CH2:21][CH2:22][CH2:17][CH2:18][CH2:19]1

Participants

3

Reactant 2

HCID 164953872-(7-bromo-5-methyl-1H-indol-3-yl)ethanamine hydrochlorideHCID 187022954-Cyclohexylphenylhydrazine hydrochloride

Product 1

HCID 187022465-Cyclohexyltryptamine hydrochloride

Procedure

5-Cyclohexyltryptamine hydrochloride was prepared (1.29 g) as described for 5-methyl-7-bromotryptamine hydrochloride in Example 4, except using 4-cyclohexylphenylhydrazine hydrochloride as starting material.

Sources & evidence

ORD record
ord-72e6ad82576b4b59b604a647582771bf
Source dataset
uspto-grants-1998_01
Patent number
US05705519

Reaction notes

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