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HRID72505

反应详情

EQUATION

反应方程式

HRID 72505 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1ccc(C2(N)CC2)cc1.Cl
HCID66824369

未命名化合物

结构：O=C(O)c1cc(Cl)cnc1N1CC(O)(c2cccc(F)c2)C1
HCID67958667

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(C2(NC(=O)c3cc(Cl)cnc3N3CC(O)(c4cccc(F)c4)C3)CC2)cc1
HCID67958825

未命名化合物

收率 66.9%

PROCEDURE

实验过程

The title compound (D161) (64.7 mg) was prepared according to the experimental procedure described in Description 146 (reaction time 1 h) starting from 5-chloro-2-(3-(3-fluorophenyl)-3-hydroxyazetidin-1-yl)nicotinic acid (D111) (63 mg, 0.195 mmol) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (D7) (44.4 mg, 0.195 mmol).

WORKUP

后处理

  1. customdescribed in Description 146 (reaction time 1 h)