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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 72509Generated: October 30, 2026

Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → HCID 67958160, compound

https://huagongshe.com/reaction/72509

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(1-aminocyclopropyl)benzoate hydrochlorideHCID 66824369—
Reactant5-Chloro-2-(3-((3-fluorophenyl)amino)azetidin-1-yl)nicotinic acidHCID 67958101—
ProductHCID 67958160HCID 6795816027.7%

Reaction Steps

The title compound (D166) (17 mg) was prepared according to the experimental procedure described in Description 144 starting from 5-chloro-2-(3-((3-fluorophenyl)amino)azetidin-1-yl)nicotinic acid (D116) (40 mg, 0.124 mmol) and methyl 4-(1-aminocyclopropyl)benzoate (D7) (28.3 mg, 0.124 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08828987B2
Source datasetuspto-grants-2014_09
ORD IDord-2dad8ab2aeac41588d058f623d10fbf7
Source noteuspto-grants-2014_09