Hydrochloric Acid → HCID 67653248, compound

Participants

Reaction Steps

A solution containing 3.55 g (6.5 mmol) of ethyl 11-{N-[2,5-di(benzoyloxy)benzoyl]amino}undecanoate (compound of Example 9) in 95 ml of ethanol was adjusted to a pH value of 3 by adding concentrated hydrochloric acid, and hydrogenated in the presence of 1.3 g of 10% palladium-on-carbon catalyst under environmental pressure. After filtering off the catalyst, the solution was evaporated under reduced pressure, the residue was thoroughly triturated with 10 ml petroleum ether and dried to obtain 1.60 g (67.3%) of the aimed compound, m.p.: 72°-74° C.

Provenance & Evidence