Ethanol, 2-amino-, 1-nitrate, nitrate (1:1) → HCID 54047217, compound

HRID 725128Notes

Reaction equation

HRID 725128 reaction equation
[C:1]([NH:4][C@@H:5]([CH2:9][O:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][O:12]1)[C:6]([OH:8])=O)(=[O:3])[CH3:2].[N+]([O-])(O)=O.[N+:21]([O:24][CH2:25][CH2:26][NH2:27])([O-:23])=[O:22]>>[N+:21]([O:24][CH2:25][CH2:26][NH:27][C:6](=[O:8])[C@H:5]([NH:4][C:1](=[O:3])[CH3:2])[CH2:9][O:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][O:12]1)([O-:23])=[O:22]

Participants

3

Reactant 2

HCID 78397Ethanol, 2-amino-, 1-nitrate, nitrate (1:1)HCID 53696763HCID 53696763, compound

Product 1

HCID 54047217HCID 54047217, compoundYield 29.8%

Procedure

The procedures of Example 1 were analogously repeated using 1.07 g of (2S)-2-acetylamino-3-(tetrahydropyran-2-yl)oxypropionic acid and 0.94 g of 2-nitrooxyethylamine nitrate to give 0.44 g of the title compound as pale yellow crystals.

Sources & evidence

ORD record
ord-71b273ae3bb045bbb7c77d0cba4ca9c2
Source dataset
uspto-grants-1998_01
Patent number
US05705527

Reaction notes

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