HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → HCID 67958766, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride | HCID 66824369 | — |
| Reactant | 2-(3-(3-Fluorophenoxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acid | HCID 67966680 | — |
| Product | HCID 67958766 | HCID 67958766 | 80.9% |
Reaction Steps
The title compound (D172) (60 mg) was prepared according to the experimental procedure described in Description 146 starting from 2-(3-(3-fluorophenoxy)azetidin-1-yl)-5-(trifluoromethyl)nicotinic acid (D121) (50 mg, 0.14 mmol) and methyl 4-(1-aminocyclopropyl)benzoate (D7) (31.95 mg, 0.14 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08828987B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-a7838005109b47cf94bd215854749c2d |
| Source note | uspto-grants-2014_09 |