HCID 10934229, compound → HCID 10923492, compound

Participants

Reaction Steps

A mixture of 2.00 g of (1S,3aS,5S,7aR)-1-hydroxymethyl-5-phenyl-7a-methylperhydroinden-3a-ol, intermediate in the synthesis of (II-ag) and 0.85 g of 5% Rhodium on alumina powder in 30 ml of methanol was hydrogenated at room temperature at 60 psi. in a Parr apparatus, for 4 hrs. The mixture was then filtered through celite and the solvent was evaporated under reduced pressure to give 1.94 g of (1S,3aS,5S,7aR)-1-hydroxymethyl-5-cyclohexyl-7a-methylperhydroinden-3a-ol as a white solid.

Provenance & Evidence