反应详情

3.0 g of 2-fluoro-3,4-dimethoxybenzyl alcohol and 5.0 g of manganese dioxide are heated under reflux for 1 hour together with 50 ml of benzene. The insoluble constituents are subsequently filtered while washing with methylene chloride. The filtrate is evaporated and the residue is recrystallized from methylene chloride/hexane. There is obtained 2-fluoro-3,4-dimethoxybenzaldehyde of m.p. 52°-54°.

1. filtrationThe insoluble constituents are subsequently filtered
2. washwhile washing with methylene chloride
3. customThe filtrate is evaporated
4. customthe residue is recrystallized from methylene chloride/hexane