(S)-tert-butyl 2-((3-fluorophenoxy)methyl)pyrrolidine-1-carboxylate → (S)-methyl 4-(1-(5-chloro-2-(2-((3-fluorophenoxy)methyl)pyrrolidin-1-yl)nicotinamido)cyclopropyl)benzoate

Beteiligte Stoffe

Reaktionsschritte

The title compound (D202) (89 mg) was prepared according to the experimental procedure described in Description 160 starting from (S)-tert-butyl 2-((3-fluorophenoxy)methyl)pyrrolidine-1-carboxylate (D44) (100 mg, 0.338 mmol) and reacting in the second step with methyl 4-(1-(2,5-dichloronicotinamido)cyclopropyl)benzoate (D97) (61.8 mg, 0.169 mmol).

Herkunft & Nachweise