HCID 86751904, compound → HCID 9808979, compound

Participants

Reaction Steps

A The reaction is carried out in a way analogous to that described in Example 2A, but from 3.3 g of tert-butyl (2RS,4SR,5RS)-1-{2-[3-(3-(benzyloxycarbonyl)phenyl)ureido]acetyl}-5-phenyl-4-(phenylsulphonyl)pyrrolidine-2-carboxylate and 0.35 g of 10% palladium-on-charcoal in 100 cm3 of ethanol. After treatment, there are obtained 1.45 g of (2RS,4SR,5RS)-3-{3-[2-(2-tert-butoxycarbonyl-5-phenyl-4-phenylsulphonyl-1-pyrrolidinyl)-2-oxoethyl]ureido}benzoic acid, melting at 213° C.

Provenance & Evidence