Hydrochloric Acid → HCID 19710211, compound

Participants

Reaction Steps

5,6-Dihydroxy-2-(di-n-propylamino)indan hydrobromide (200 mg, 0.6 mmol) was reacted with 1,2-dibromoethane (0.05 mL, 0.66 mmol) under the same reaction conditions as Example 4. The crude material was chromatographed (200 g silica gel) eluting with methylene chloride/methanol (9:1) to yield an oil. The oil was converted into the HCl salt and recrystallized using methanol/ethyl acetate/ether: mp 210°-215° C.

Provenance & Evidence