Sodium Hydroxide → HCID 19710214, compound

HRID 725932Notes

Reaction equation

HRID 725932 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[CH2:10][CH:9]([N:16]([CH2:20][CH2:21][CH3:22])[CH2:17][CH2:18][CH3:19])[CH2:8]2)([O:3]C)=[O:2].[OH-].[Na+]>CO.O>[C:1]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[CH2:10][CH:9]([N:16]([CH2:17][CH2:18][CH3:19])[CH2:20][CH2:21][CH3:22])[CH2:8]2)([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19710195HCID 19710195, compound

Product 1

HCID 19710214HCID 19710214, compound

Reagents, catalysts & solvents 1

HCID 22242641Methanol--water (1/1)Solvent

Procedure

A solution of 5-carbomethoxy-6-methoxy-2-(di-n-propylamino)indan (Example 57) in methanol/water is hydrolyzed with sodium hydroxide. After work-up and purification, the title compound is obtained.

Workup

  1. customAfter work-up and purification

Sources & evidence

ORD record
ord-34273c8fedd94d2c99c1a0033968f00e
Source dataset
uspto-grants-1998_01
Patent number
US05708018

Reaction notes

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