1-Methyl-4-piperidone → HCID 22611387, compound

HRID 725972Notes

Reaction equation

HRID 725972 reaction equation
[CH3:1][N:2]([S:4]([NH:7][C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[NH:13][CH:12]=[CH:11]2)(=[O:6])=[O:5])[CH3:3].[CH3:17][N:18]1[CH2:23][CH2:22][C:21](=O)[CH2:20][CH2:19]1>>[CH3:3][N:2]([S:4]([NH:7][C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[NH:13][CH:12]=[C:11]2[C:21]1[CH2:22][CH2:23][N:18]([CH3:17])[CH2:19][CH:20]=1)(=[O:6])=[O:5])[CH3:1]

Participants

3

Reactant 2

HCID 740491-Methyl-4-piperidoneHCID 22611354HCID 22611354, compound

Product 1

HCID 22611387HCID 22611387, compoundYield 72.8%

Procedure

Beginning with 1.17 gm (4.89 mMol) 5-(N,N-dimethylamino)sulfonylamino-1H-indole and 0.78 mL (6.4 mMol) 1-methyl-4-piperidone, 1.19 gm (72.6%) of the title compound were recovered as a pale yellow powder.

Sources & evidence

ORD record
ord-1fce311d3c3147c5a4bab0dd11b75b61
Source dataset
uspto-grants-1998_01
Patent number
US05708008

Reaction notes

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