1-Ethylpiperidin-4-one → HCID 22611487, compound

HRID 725973Notes

Reaction equation

HRID 725973 reaction equation
[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[CH:9]2)(=[O:4])=[O:3].[CH2:15]([N:17]1[CH2:22][CH2:21][C:20](=O)[CH2:19][CH2:18]1)[CH3:16]>>[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[C:9]2[C:20]1[CH2:21][CH2:22][N:17]([CH2:15][CH3:16])[CH2:18][CH:19]=1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 771591-Ethylpiperidin-4-oneHCID 10036020HCID 10036020, compound

Product 1

HCID 22611487HCID 22611487, compoundYield 59.1%

Procedure

Beginning with 1.50 gm (7.1 mMol) 5-methanesulfonylamino-1H-indole and 1.25 mL (9.3 mMol) 1-ethyl-4-piperidone, 1.34 gm (58.8%) of the title compound were recovered as a light yellow, crystalline powder.

Sources & evidence

ORD record
ord-c1c9b0be8a5149c9a43daaa11ea06ac7
Source dataset
uspto-grants-1998_01
Patent number
US05708008

Reaction notes

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