1-Propyl-4-piperidone → HCID 22611284, compound

HRID 725974Notes

Reaction equation

HRID 725974 reaction equation
[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[CH:9]2)(=[O:4])=[O:3].[CH2:15]([N:18]1[CH2:23][CH2:22][C:21](=O)[CH2:20][CH2:19]1)[CH2:16][CH3:17]>>[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[C:9]2[C:21]1[CH2:22][CH2:23][N:18]([CH2:15][CH2:16][CH3:17])[CH2:19][CH:20]=1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 900061-Propyl-4-piperidoneHCID 10036020HCID 10036020, compound

Product 1

HCID 22611284HCID 22611284, compoundYield 88.7%

Procedure

Beginning with 1.50 gm (7.1 mMol) 5-methanesulfonylamino-1H-indole and 1.4 mL (9.3 mMol) 1-propyl-4-piperidone, 2.1 gm (88.2%) of the title compound were recovered as a yellow powder.

Sources & evidence

ORD record
ord-268da594dde8414e98ce639a5d7c0078
Source dataset
uspto-grants-1998_01
Patent number
US05708008

Reaction notes

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