1-Butyl-4-piperidone → HCID 22611212, compound

HRID 725976Notes

Reaction equation

HRID 725976 reaction equation
[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[CH:9]2)(=[O:4])=[O:3].[CH2:15]([N:19]1[CH2:24][CH2:23][C:22](=O)[CH2:21][CH2:20]1)[CH2:16][CH2:17][CH3:18]>>[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[C:9]2[C:22]1[CH2:23][CH2:24][N:19]([CH2:15][CH2:16][CH2:17][CH3:18])[CH2:20][CH:21]=1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 899951-Butyl-4-piperidoneHCID 10036020HCID 10036020, compound

Product 1

HCID 22611212HCID 22611212, compoundYield 84.8%

Procedure

Beginning with 1.0 gm (4.76 mMol) 5-methanesulfonylamino-1H-indole and 0.96 gm (6.2 mMol) 1-butyl-4-piperidone, 1.4 gm (84.8%) of the title compound were recovered as a yellow powder.

Sources & evidence

ORD record
ord-49f99e33f8d84f98a6dae17dffa6fcf6
Source dataset
uspto-grants-1998_01
Patent number
US05708008

Reaction notes

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