Propyl isocyanate → HCID 22611228, compound

HRID 725988Notes

Reaction equation

HRID 725988 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[CH2:18]([N:21]=[C:22]=[O:23])[CH2:19][CH3:20]>>[CH2:18]([NH:21][C:22]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:23])[CH2:19][CH3:20]

Participants

3

Reactant 2

HCID 61033Propyl isocyanateHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611228HCID 22611228, compound

Procedure

Beginning with 15.0 mg 0.0655 mMol) 5-amino-3-(1-methyl-piperidin-4-yl)-1H-indole and 11.1 mg (0.131 mMol) propyl isocyanate, 5.8 mg of the title compound were recovered.

Sources & evidence

ORD record
ord-bacff5464acd4c218677037467870b41
Source dataset
uspto-grants-1998_01
Patent number
US05708008

Reaction notes

Loading…