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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 726000Generated: November 1, 2026

Phenyl Isothiocyanate → N-phenyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)thiourea

https://huagongshe.com/reaction/726000

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl IsothiocyanateHCID 7673—
Reactant3-(1-Methylpiperidin-4-yl)-1h-indol-5-amineHCID 11831220—
ProductN-phenyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)thioureaHCID 2261150371%

Reaction Steps

Beginning with 15.0 mg (0.0655 mMol) 5-amino-3-(1-methyl-piperidin-4-yl)-1H-indole and 13.26 mg (0.098 mMol) phenyl isothiocyanate, 16.8 mg (71%) of the title compound were recovered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05708008
Source datasetuspto-grants-1998_01
ORD IDord-076e04f1814c4cc28aac25a730834a30
Source noteuspto-grants-1998_01