Isobutyric Acid → HCID 22611371, compound

HRID 726025Notes

Reaction equation

HRID 726025 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[C:18](O)(=[O:22])[CH:19]([CH3:21])[CH3:20]>>[CH3:20][CH:19]([CH3:21])[C:18]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:22]

Participants

3

Reactant 2

HCID 6590Isobutyric AcidHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611371HCID 22611371, compoundYield 79%

Procedure

Beginning with 12.0 mg (0.05 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 8.8 mg (0.10 mMol) isobutyric acid, 11.8 mg (79%) of the title compound were recovered.

Sources & evidence

ORD record
ord-19f01b0202cf44b6b6d931903b210b7f
Source dataset
uspto-grants-1998_01
Patent number
US05708008

Reaction notes

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