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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 726071Generated: October 26, 2026

3-Methyl-2-thenoic acid → 5-(3-methyl-2-thienoyl)amino-3-(1-methylpiperidin-4-yl)-1H-indole

https://huagongshe.com/reaction/726071

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-2-thenoic acidHCID 90269—
Reactant3-(1-Methylpiperidin-4-yl)-1h-indol-5-amineHCID 11831220—
Product5-(3-methyl-2-thienoyl)amino-3-(1-methylpiperidin-4-yl)-1H-indoleHCID 2261147590.5%

Reaction Steps

Beginning with 7.0 mg (0.03 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 12.8 mg (0.09 mMol) 3-methyl-2-thienoic acid, 9.6 mg (90%) of the title compound were recovered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05708008
Source datasetuspto-grants-1998_01
ORD IDord-a3e4e748cb4344149a863ca7c19d2dab
Source noteuspto-grants-1998_01