HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Benzyloxyindole → 5-(Benzyloxy)-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Benzyloxyindole | HCID 14624 | — |
| Reactant | 4-Piperidone | HCID 33721 | — |
| Product | 5-(Benzyloxy)-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 23290462 | — |
Reaction Steps
Starting with 5.0 gm (22 mMol) 5-benzyloxyindole and 6.88 gm (45 mMol) 4-piperidone.HCl.H2O, 6.53 gm (97.6%) of 5-benzyloxy-3-[1,2,5,6-tetrahydro-4-pyridinyl]-1H-indole were recovered as a light yellow solid by the procedure described in Preparation I. The material was used in the subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05708008 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-4ec9c7a032604034a378292a6bf4047b |
| Source note | uspto-grants-1998_01 |