4-Bromo-3-chloro-3,4,4-trifluorobutanoic acid → 3,4,4-Trifluoro-3-butenoic acid

HRID 726118Notes

Reaction equation

HRID 726118 reaction equation
Br[C:2]([F:11])([F:10])[C:3](Cl)([F:8])[CH2:4][C:5]([OH:7])=[O:6]>[Zn]>[F:8][C:3](=[C:2]([F:11])[F:10])[CH2:4][C:5]([OH:7])=[O:6]

Participants

3

Reactant 1

HCID 109121274-Bromo-3-chloro-3,4,4-trifluorobutanoic acid

Product 1

HCID 152391743,4,4-Trifluoro-3-butenoic acid

Reagents, catalysts & solvents 1

HCID 23994ZincCatalyst

Procedure

Dehalogenation of 4-bromo-3-chloro-3,4,4-trifluorobutanoic acid (VIII) with zinc using conditions analogous to those disclosed in the literature to obtain the desired 3,4,4-trifluoro-3-butenoic acid (IV); or

Sources & evidence

ORD record
ord-c07b8f424758419ab5554ad2b9124ce6
Source dataset
uspto-grants-1998_01
Patent number
US05708032

Reaction notes

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