HCID 19710466, compound → HCID 19710471, compound

Participants

Reaction Conditions

Reaction Steps

20 g (0.045 mol) N,N'-bis(2-nitrophenyl)-1,12-diaminododecane are dissolved in 100 ml concentrated hydrochloric acid, and 43 g (0.19 mol) stannochloride dihydrate dissolved in 50 ml concentrated hydrochloric acid are added. The mixtured is heated to approxiately 100° C. while stirred, and after three hours the product separated off is cooled. The water phase is separated off, and the product is suspended in 200 ml hot water, whereafter it is poured into 500 ml 2M sodium hydroxide. The released tetraamine is extracted twice with 150 ml methylchloride, and the organic phase is dried over magnesium sulphate and evaporated, whereby the product is crystallized. Yield 17.30 g (100%), melting point 85° to 88° C.

Provenance & Evidence