HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Quinolinecarboxylic acid → 1,2,3,4-Tetrahydroquinoline-8-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Quinolinecarboxylic acid | HCID 66582 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1,2,3,4-Tetrahydroquinoline-8-carboxylic acid | HCID 2785589 | 92% |
Reaction Steps
A solution of quinoline-8-carboxylic acid (85 mg) in ethanol (15 ml) was hydrogenated over PtO2 (250 mg) at 50 psi and room temperature for 2 hours. The catalyst was removed by filtration through keiselguhr and the filtrate concentrated in vacuo to afford the title compound (80 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05708174 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-ae55b80b9fe04c998a452701a92f033d |
| Source note | uspto-grants-1998_01 |