Cyclopentylacetic acid → HCID 178520196, compound

HRID 726223Notes

Reaction equation

HRID 726223 reaction equation
[CH:1]1([CH2:6][C:7]([OH:9])=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:10]1[CH:14]=[C:13]([CH2:15][CH2:16][CH2:17][CH2:18][NH2:19])[N:12]=[CH:11]1>>[NH:10]1[CH:14]=[C:13]([CH2:15][CH2:16][CH2:17][CH2:18][NH:19][C:7](=[O:9])[CH2:6][CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5]2)[N:12]=[CH:11]1

Participants

3

Reactant 2

HCID 71606Cyclopentylacetic acidHCID 178510959HCID 178510959, compound

Product 1

HCID 178520196HCID 178520196, compound

Procedure

The preparation is carried out as in Example 1 with 2-cyclopentylacetic acid and 4-(1H-imidazol-4-yl)butanamine. The title compound is extracted from water with diethyl ether and recrystallized in the hydrogenmaleate form from ethanol/diethyl ether.

Workup

  1. extractionThe title compound is extracted from water with diethyl ether
  2. customrecrystallized in the hydrogenmaleate form from ethanol/diethyl ether

Sources & evidence

ORD record
ord-2a9ec9a6a1584c37b9b58a38f3760273
Source dataset
uspto-grants-1998_01
Patent number
US05708171

Reaction notes

Loading…