HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → Dihydrobromide monohydrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | HCID 178418616 | HCID 178418616 | — |
| Reactant | HCID 178520346 | HCID 178520346 | — |
| Product | Dihydrobromide monohydrate | HCID 21713259 | — |
| Product | HCID 178420566 | HCID 178420566 | — |
Reaction Steps
0.5 g (4.4 mmol) of 4-(2-hydroxyethyl)-1H-imidazole and 0.49 g (44.4 mmol) of 2-mercaptopyridine are brought to reflux in 5 ml of 47% aqueous HBr for 24 h. The solvent is removed azeotropically with isopropanol under reduced pressure to provide the title compound in the form of a dihydrobromide monohydrate salt which, after crystallization from isopropanol, melts at 189°-190° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05708171 |
| Source dataset | uspto-grants-1998_01 |
| ORD ID | ord-eb7e2ed7efb6461b8167f87db4bacec8 |
| Source note | uspto-grants-1998_01 |