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1-(2-Methoxyphenyl)piperazine → Nan 190
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| 反応物 | N-(4-Bromobutyl)phthalimide | HCID 93575 | — |
| 反応物 | 1-(4-Aminobutyl)-4-(2-methoxyphenyl)piperazine | HCID 10999903 | — |
| 生成物 | Nan 190 | HCID 4431 | 84.3% |
反応手順
4-[4-(2-methyloxyphenyl)piperazinyl]butylamine: according to the method of claim 1, N-(4-bromobutyl)phthalimide and 2-methyloxyphenyl-piperazine was used in reaction to produce N-{4-[4-(2-methyloxyphenyl)piperazinyl]butyl}phthalimide, which was then reacted with hydrazine hydrate. The yield was: 84.3%. Hydrochloride salt had a mp: 173-175° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08829001B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-00c4f5ce7b76428bacf0d4d57cbaa035 |
| 出典メモ | uspto-grants-2014_09 |