HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 726328Generated: October 29, 2026
8-[2,6-dichloro-3-[N-methyl-N-[4-(methylcarbamoyl)cinnamoylglycyl)amino]benzyloxy]-2-methylquinoline → Sulfuric Acid
https://huagongshe.com/reaction/726328
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 8-[2,6-dichloro-3-[N-methyl-N-[4-(methylcarbamoyl)cinnamoylglycyl)amino]benzyloxy]-2-methylquinoline | HCID 54496054 | — |
| Reactant | Sulphuric acid ethanol | HCID 73950302 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Sulfuric Acid | HCID 1118 | — |
| Product | 8-[2,6-dichloro-3-[N-methyl-N-[4-(methylcarbamoyl)cinnamoylglycyl)amino]benzyloxy]-2-methylquinoline | HCID 54496054 | — |
Reaction Steps
To a suspension of 8-[2,6-dichloro-3-[N-methyl-N-[4-(methylcarbamoyl)cinnamoylglycyl]amino]benzyloxy]-2-methylquinoline (149.7 mg) in ethanol (1.5 ml) was added 1M sulfuric acid-ethanol solution (253.1 μl) at ambient temperature, and the mixture was warmed at 90° C. and then stirred for 1 hour at ambient temperature. The solvent was removed in vacuo to give sulfuric acid salt of 8-[2,6-dichloro-3-[N-methyl-N-[4-(methylcarbamoyl)cinnamoylglycyl]amino]benzyloxy]-2-methylquinoline (144.5 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05708173 |
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| Source dataset | uspto-grants-1998_01 |
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| ORD ID | ord-1526c0c2ef1d4570b7d05ce954d1ed35 |
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| Source note | uspto-grants-1998_01 |
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