4-Fluorophenyl chloroformate → HCID 54481256, compound

HRID 726345Notes

Reaction equation

HRID 726345 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10]1[CH2:9][CH2:8][CH:7]([N:15]([CH3:17])[CH3:16])[CH2:6][C:5]2=1.Cl[C:19]([O:21][C:22]1[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=1)=[O:20]>>[F:28][C:25]1[CH:26]=[CH:27][C:22]([O:21][C:19]([NH:1][C:2]2[CH:3]=[C:4]3[C:12](=[CH:13][CH:14]=2)[NH:11][C:10]2[CH2:9][CH2:8][CH:7]([N:15]([CH3:17])[CH3:16])[CH2:6][C:5]3=2)=[O:20])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 27332564-Fluorophenyl chloroformateHCID 226115606-amino-3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazole

Product 1

HCID 54481256HCID 54481256, compoundYield 40%

Procedure

Beginning with 6.0 mg (0.026 mMol) 6-amino-3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazole and 4.8 mg (0.0273 mMol) 4-fluorophenyl chloroformate, 3.8 mg (40%) of the title compound were recovered.

Sources & evidence

ORD record
ord-e4956db38a374d6c9b987038aa678140
Source dataset
uspto-grants-1998_01
Patent number
US05708187

Reaction notes

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