Ammonium formate → 2,3-Dihydro-1,4-benzodioxin-5-amine

Participants

Reaction Steps

Ammonium formate (3.40 g, 0.054 mol) and 10% passadium on charcoal (1.44 g) were added to a stirred solution of the product of Example 1 (2.45 g, 0.0135 mol) in methanol (15 ml). After the considerable effervescence had ceased, the mixture was filtered, evaporated in vacuo and triturated with acetonitrile. The residue was purified by chromatography (silica; ether) to give the product (1.51 g).

Provenance & Evidence