Ethyl Acetate → HCID 10970791, compound

Participants

Reaction Steps

To a solution of 5-(4-fluorophenyl)-4-(4-(methylthio)phenyl)thiophene-2-carboxylic acid methyl ester (5.60 g) in CH2Cl2 (84.0 mL) at 0° C. was added portionwise m-CPBA 50 to 60% (5.39 g). After TLC showed completion (50% EtOAc in hexane), the reaction mixture was extracted with saturated NaHCO3, dried over Na2SO4, filtered and evaporated to dryness to provide the title compound as a white foam (5.00 g).

Provenance & Evidence