Hydrochloric Acid → HCID 44289234, compound

Participants

Reaction Steps

Deprotection of the amino acid was effected in refluxing 6M HCl for 6 h. Evaporation of the solvent gave a residue which was put onto an acidic ion-exchange resin and eluted with water. Collection of ninhydrin-sensitive fractions and evaporation of solvent gave (R)-α-amino-3-phosphonomethyl-7-ethoxy-2-quinolinepropanoic acid. 13C-NMR (D2O plus NH3 vapours): δ (ppm) 174.7, 158.7, 156.3, 146.3, 138.0, 137.9, 128.6, 122.6, 118.8, 106.2, 64.4, 54.1, 34.2, 34.0, 32.8, 13.9.

Provenance & Evidence