1,4-Dioxane → HCID 53944603, compound

Participants

Reaction Steps

SeO2 (0.56 g, 5.06 mmol) was added to a solution of 3-(diethylphosphonomethyl)-6,7-dimethoxy-2-methylquinoline (1.79 g, 5.06 mmol) in dioxane (25 ml). The mixture was refluxed for 75 min, filtered and concentrated. The remaining oil was purified by chromatography to give 1.48 g 3-(diethylphosphonomethyl)-6,7-dimethoxyquinoline-2-carboxaldehyde.

Provenance & Evidence