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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 726639Generated: October 29, 2026

HCID 53681954, compound → HCID 53793415, compound

https://huagongshe.com/reaction/726639

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 53681954HCID 53681954—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 53793415HCID 5379341581.7%

Reaction Steps

A mixture of α-(benzyloxycarbonylamino)-3-(diethylphosphonomethyl)-6,7-dimethoxy-2-quinolineacrylic acid methyl ester (0.14 g, 0.25 mmol) and a catalytic amount of palladium on charcoal (10%) in MeOH (10 ml) was hydrogenated at 4 bar for 20 h. Filtration and chromatographic purification gave 0.09 g α-amino-3-(diethylphosphonomethyl)-6,7-dimethoxy-2-quinolinepropanoic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05710139
Source datasetuspto-grants-1998_01
ORD IDord-125e601c34bd41b4b53d1cb78c903d15
Source noteuspto-grants-1998_01